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Target peptide quantification : allows construction of a direct cerebral pharmacokinetic curve, compared to plasma to calculate the brain/plasma ratio

These therapeutic approaches could also be extended to other neurodegenerative conditions affecting the CNS

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This technological advancement represents a significant step forward, as it may eventually allow researchers to monitor treatment-induced changes in neuroinflammation regardless of whether the therapeutic target is neuronal, astrocytic, or microglial in nature