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Description

Sep Sci Technol

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Additionally, the absence of PARP-1 in mice resulted in a notable decrease in the occurrence of colorectal cancer caused by oxymethane (AOM) and dextran sulfate sodium (DSS)

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Engineering CD276/B7-H3-targeted antibody-drug conjugates with enhanced cancer-eradicating capability

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doi: 10.3389/fnut.2024.1290540

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Together, these data suggest that free oxaliplatin is strongly inactivated by biothiols, probably with dominant extracellular conjugate formation, while BSO-OxOAc is protected against extracellular inactivation based on its prodrug nature

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