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D), the stress hormone cortisol, and sex hormones such as testosterone and estrogen [5]

Elevated GH secretion drives downstream IGF-1 production, mediated primarily through hepatic GH receptor signalling, and the GH/IGF-1 axis effects of ipamorelin including anabolic signalling in skeletal muscle, lipolytic activity in adipose tissue, and effects on bone metabolism have been studied in multiple preclinical models

Safety profiles, dosing, and regulatory approvals differ between the two substances

A disorder cutoff of 0.5 was used to perform the search

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