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Given the wealth of clinically available agents that target one-carbon metabolism, these new findings could present opportunities for translation into precision cancer medicine

MarktelSScaramuzzaSCicaleseMPGiglioFGalimbertiSLidonniciMRet alIntrabone hematopoietic stem cell gene therapy for adult and pediatric patients affected by transfusion-dependent ss-thalassemia

Is increased tissue ferritin a risk factor for atherosclerosis and ischaemic heart disease

PGC-1 regulates DRP1 expression by enriching in the promoter region to downregulate DRP1 expression and further inhibits mitochondrial fission ( via deacetylating and activating OPA1 (Samant et al., 2014)