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A clinical study involving 50 human subjects using 4% Syn-AKE topically twice daily for 28 days demonstrated[5]: Wrinkle depth reduction of up to 52% on forehead expression lines Smoothing effect measurable in 80% of participants Wrinkle reduction evident in 73% of subjects Superior efficacy compared to acetyl hexapeptide-8 (Argireline) in head-to-head comparison Skin surface measurement studies using profilometry showed improvements in skin roughness parameters (Ra, Rz, and Rt measurements), with effects visible as early as 1-2 hours post-application continuing through 28 days of use[5]

Karlstad O, Starup Linde J, Vestergaard P, et al

Regular system maintenance and testing are also essential to ensure it functions correctly

WHO (2022) Obesity and overweight

This reduced muscle activity is what smooths out facial wrinkles and, in this off-label case, lets the nasal tip lift slightly

Pimples are often caused by multiple reasons like excess sebum production, clogged pores, hormonal changes & environmental pollution