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This work was supported by research grant from Cour Pharmaceuticals, Wistar CancerCenter Support NIH grant P30 CA10815, and NIH grant CA165065 LD - conducted most of the experiments, analyzed data, wrote initial manuscript, PV,TK - conducted experiments, analyzed data, TM, JRP, AE, MTB, JJP - designed experiments, analyzed data, provided materials, wrote MS

[DOI] [PubMed] [PMC] Lee DY, Kim EH

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Upon ligand binding, VEGFR-2 undergoes dimerization and autophosphorylation, initiating downstream signaling cascades that include the phosphoinositide 3-kinase (PI3K)/Akt and the mitogen-activated protein kinase (MAPK)/ERK pathways

doi: 10.1093/ije/dyw078 21 CamiloV.SugiyamaT.TouatiE

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