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Advances in precision medicine and biomarker discovery hold promise for enhancing lithiums clinical impact and tailoring treatment to individual biological profiles, ensuring that this historically significant drug remains at the forefront of neuropsychiatric therapeutics

doi: 10.1016/j.braindev.2004.08.002 66 NakamuraM.MiuraA.NagahataT.ShibataY.OkadaE.OjimaT

By decreasing oxidative stress, researchers have suggested that the risk of cancer, parkinson's disease, alzheimer's disease, etc

RSL3 contains a reactive chloroacetamide moiety that makes it a potent and irreversible GPX4 inhibitor, although its poor solubility and poor absorption, distribution, metabolism, and excretion (ADME) properties limit its effectiveness in in-vivo studies [22]