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Interestingly, we found that -syn knockout mice or siP-Syn mice were resistant to a chronic hypoxia-induced decline in PP2A activity, showing no increase in the p-PP2A/PP2A ratio after hypoxia (Fig

While iron depletion appears to mediate some of the effects of frataxin inhibition, the two processes also involve distinct mechanisms

Biddinger, K

horneri therapy significantly enhanced both total AMPK and phosphorylated AMPK (p-AMPK) levels (Fig

That said, the gene expression data involving hundreds of neuronal genes suggests this could become a significant application area as human studies catch up