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Specifically:[2] helps in fat metabolism , contributes to the protection of cells from fatty infiltration, while favoring muscle recovery

doi: 10.1128/jb.184.14.4044-4047.2002 53 WuW.-K.ChenC.-C.LiuP.-Y.PanyodS.LiaoB.-Y.ChenP.-C.et al

Gharibi V, Mokarami H, Cousins R, Jahangiri M, Eskandari D

GABA is made from glutamate, an excitatory neurotransmitter, using the GAD1 and GAD2 enzymes with the active form of vitamin B6 (P5P) as a cofactor

In a study of 156 patients with CHF, in which all patients were given conventional medications for the disease, those who were also given 1.2-2 g of berberine per day experienced improvements in ejection fraction, exercise capacity, and dyspnea, as well as a decrease in the frequency of complex premature ventricular contractions (PVCs), compared to the placebo group