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Notably, previous studies have confirmed that the aforementioned gut bacteria regulated by dietary fiber (e.g., Bifidobacterium, Lactobacillus, Faecalibacterium ) are closely associated with depression ( 5.3 Potential mechanisms of dietary fiber affecting depression (1) Mood regulation mediated by SCFAs produced via gut microbiota fermentation Dietary fiber cannot be digested and absorbed by the human body but can be partially or fully fermented by gut microbiota (122)

343 According to a 2020 systematic review and meta-analysis that included 60 randomized controlled trials with a total of 4,129 patients, omega-3 fatty acid supplementation appeared to decrease the incidence of cardiovascular death by 55% in CKD patients on hemodialysis, though it did not appear to reduce mortality overall

doi: 10.1007/s12551016-02444 260 El-MahroukSREl-GhiatyMAEl-KadiAOS

Mitochondria contain multiple copies of their own genome, mitochondrial DNA (mtDNA), which encodes for 13 polypeptides of the OXPHOS and respiratory chain, as well as two ribosomal RNAs and 22 transfer RNAs necessary for translation of polypeptides inside mitochondria

Brain Sci 13(2):345

& Ohm, J