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doi: 10.1016/j.jep.2008.11.011

These mutations are referred to as CRIM-negative mutations where CRIM means cross-reactive immunologic material. Type I mutations represent the largest percentage of mutations in AIP patients, consisting of approximately 85% of mutations

"Metabolism of ketonic acids in animal tissues"

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Another type of post-translational modification is methylation by arginine methyltransferases (PRMTs), in which arginine can be methylated to either monomethylated arginine or dimethylated arginine

the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) step can itself be restrained by reductive stress, i.e., an elevated NADH:NAD ratio