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It's going to be mayhem

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3.5 Neurotrophic deficits and impaired hippocampal neurogenesis The diminishment of neurotrophic signaling, especially that related to brain-derived neurotrophic factor (BDNF), stands as a defining characteristic of depression

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Primary applications: wound healing (closure kinetics, collagen organization, tensile strength), tendon and ligament regeneration (Achilles transection, biomechanical testing), gastroprotection (NSAID protection, mucosal barrier, fistula healing), angiogenesis (HUVEC tube formation, VEGF expression, CAM assays), neuroprotection (gut-brain axis, neuroinflammatory reduction), and inflammation studies (cytokine modulation, ERK1/2 pathway)

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DSIP was administered intravenously to patients for 5 consecutive days, followed by 5 additional injections every 4872 hours

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(PubMed) Van Dam F, Van Gool WA

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