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Wei Hu, Zhi Yang, Wenwen Yang, Mengzhen Han, Baoping Xu, Zihao Yu, Mingzhi Shen, Yang Yang, Roles of forkhead box O (FoxO) transcription factors in neurodegenerative diseases: A panoramic view, Progress in Neurobiology, Volume 181, 2019, 101645, ISSN 0301-0082,

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The total flushing volume should not be too large to prevent microbial damage

doi:10.1073/pnas.0908686106

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The increased cost reflects the longer treatment time, medical supplies, nursing oversight, and the ability to include multiple nutrients in one session