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Pregnant women, or women planning pregnancy during the study period, were also excluded

Also, physical and exercise-based therapies have not been evaluated in children receiving CIPN-inducing drugs

Zaki European Journal of Gastroenterology & Hepatology .2019

Monocytes play an important role in clearing infections by detecting PAMPs, phagocytosing/presenting antigens, and producing pro-inflammatory cytokines/chemokines to help recruit other leukocytes to the site of infection

W., Van Zonneveld, M., Ros, L., Pea, K., Mueller-Seitz, E., & Petz, M

As shown in Figure 3, inhibitors of NF-B and/or Akt/GSK3 pathway such as 9-methylstreptimidone (Figure 3A), 8-hydroxy verrucarin A (Figure 3C) and chrysomycin A (which has been identified twice in the screening) (Figure 3D) were able to decrease H 2 S production (upper panel), although 8-hydroxy verrucarin A and chrysomycin A also affected cell viability (lower panel)