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doi: 10.1080/08830185.2019.1609962 13 NonakaMKimuraA

35 In the Alb-uPA mouse model, uPA, which is controlled by an albumin promoter, converts plasminogen into plasmin inside hepatocytes, causing proteolysis and apoptosis

For example, cationic metallic nanoparticles are being used for gene delivery because they can easily bind to anionic DNA/RNA [136]

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If you want a deeper dive into the delivery system itself, All About Liposomes explains how liposomal technology supports absorption

Engineering exosomes as refined biological nanoplatforms for drug delivery