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Smits RS, MackenzieProctor R, Yazdani A, Stankiewicz MT, Jordan V, Showell MG, et al

193 The microbial metabolites are likely the most significant contributors to systemic inflammation and subsequent neuroinflammation

doi: 10.1016/j.bbamcr.2017.03.004

Hybrid immunity versus hybrid harms: an immunologic paradox Once it became clear that the mRNA products could not provide durable sterilizing immunity, a new rationale emerged, one centered around the concept of hybrid immunity: the enhanced immunological responses resulting from the combined exposure to mRNA vaccination and the infection, producing stronger immunity when compared to either exposure alone

The result revealed that HIF-1 specifically targeted the promoter of GPX4 to positively regulate the luciferase activity (Fig