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10.1172/JCI99987 41

This is thought to be an important barrier to achieving functional cure, but it remains to be seen whether this will continue to be the case as better treatments are developed

PubMed DOI Krivic A, Anic T, Seiwerth S, et al

doi: 10.1158/1078-0432.CCR-07-5212 165 HahnelPSThalerSAntunesEHuberCTheobaldMSchulerM

10.1182/blood-2015-08-663245 105 WalshT

When copper metabolism is disrupted, either through excess copper or copper deficiency, it can trigger abnormal immune responses, thereby exacerbating neuronal damage, especially in neurodegenerative diseases such as ischemic stroke (200)