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PCD is mainly characterized by chronic airway infections, rhinosinusitis, and bronchiectasis in consistence with the presence of motile cilia lining the surface of the respiratory airways and essential for mucus clearing (Figure 4A)

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Furthermore, CLA supplementation (78% total CLA, with 37% of the oil as c9, t11 isomers and 37% as t10, c12 isomers) for 6 weeks at a dose of 5.6 g/day had no effect on physical performance in young athletes, as assessed by VO2 max, physical working capacity, and gas exchange threshold [99]

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Major research showed that immune responses play a crucial role in the severity of pathogenesis of COVID-19 [36,37,38]