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Understanding this balance provides critical insights into tumor biology and opens new avenues for the development of anti-angiogenic therapies aimed at improving patient outcomes in GI cancers ( 3 Vascular disruption strategies 3.1 Molecular mechanisms of vascular disruption The molecular mechanisms underlying vascular disruption are complex and multifaceted, primarily involving the regulation of angiogenesis, which is the formation of new blood vessels from pre-existing ones

4) Underexplored therapeutic strategies and model limitations: Preclinical studies have relied on in vitro mesangial cell models and lack validated animal models that fully recapitulate human IgA nephropathys pathological features (e.g., glomerular IgA1 deposition and mesangial proliferation)

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The add-on effect of Lactobacillus plantarum PS128 in patients with Parkinsons disease: a pilot study

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