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This promotes local PI3P synthesis and provides a platform for recruiting autophagy precursor proteins, such as DFCP1 and WIPI1, thereby initiating isolation membrane nucleation and elongation [95]

AP site (apurinic/apyrimidinic (AP) site), APE1 (AP endonuclease 1), dRP (5 2-deoxyribose 5-phosphate), BER (base excision repair), FEN1 (flap endonuclease 1), DNA2 (DNA replication ATP-dependent helicase/nuclease) 13.2.4 Glutathione Peroxidase 1 Glutathione peroxidase 1 (GPX1) plays an important role in mitochondrial antioxidant defense by decomposing hydrogen peroxide into water (Fig

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Suppression of 3MST activity by siRNA decreased basal energetic parameters and prevented the stimulating effect of 3MP on mitochondrial bioenergetics 55