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Sahin B, Hawasli AH, Greene RW et al (2008) Negative regulation of cyclin-dependent kinase 5 targets by protein kinase C

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Urinary biomarkers, such as 2M, N-acetyl--D-glucosaminidase (NAG), and malondialdehyde, correlate strongly with arsenic exposure and serve as non-invasive tools for the early detection of renal dysfunction

27 Conversely, ascorbate deficiency has been associated with decreases in glutathione concentrations in humans

Hesperidin improves hepatic steatosis, hepatic enzymes, and metabolic and inflammatory parameters in patients with nonalcoholic fatty liver disease: a randomized, placebocontrolled, doubleblind clinical trial

Therapeutic Leverage Points Across Biomarker Pathways Given the interconnectivity of CIRS biomarkers, effective modulation requires targeting nodal regulators rather than isolated markers