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Many practitioners report sustained benefits over extended treatment periods without requiring dose escalation

From research conducted on the Dutch famine cohort, it is known that the periconceptional period (before conception until early pregnancy) is crucial for establishing and maintaining epigenetic marks

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Injected directly into muscle tissue, the nutrients gradually absorb into the bloodstream, increasing their bioavailability

doi: 10.1016/j.fertnstert.2004.10.010 Chiara De Luca, Elena V

however, the clinical effect was marginal and patient preference did not differ from placebo