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doi:10.1186/s12974-017-1026-z

Cell penetrating peptides-functionalized Licochalcone-A-loaded PLGA nanoparticles for ocular inflammatory diseases: evaluation of in vitro anti-proliferative effects, stabilization by freeze-drying and characterization of an in-situ forming gel

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Let's be direct about this: If your research model requires continuous compound presence during active testingfor example, acute cognitive performance assessment during drug administrationdaily or even twice-daily dosing makes sense