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Moreover, the aerobic oxidation of acetyl-CoA in mitochondria is affected by NADH and succinic acid [39]

Thus, deciphering the mechanistic actions of NMN in each subcellular compartment remains a challenge to be solved

Poewe W, et al

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[DOI] [PMC free article] [PubMed] [Google Scholar] 389.Inamoto S, Itatani Y, Yamamoto T, Minamiguchi S, Hirai H, Iwamoto M, et al

Continuing challenges are the incorrect, vague or ambiguous annotations in online gene databases, in addition to annotations based on older nomenclature thus does not easily correspond with current literature 41,45