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Melanin is produced by melanocytes and transferred to these cells as they form meaning any shift in the type or amount of melanin being produced only becomes visible once the newly-formed cells reach the surface and the older, differently-pigmented cells have shed away

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Exclusion criteria included: (1) preprints, editorials, commentaries, or conference abstracts without peer review

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Silicone breast implants are medical-grade silicone shells filled with cohesive silicone gel