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Medication options strongly depend on the treatment of specific symptoms

Arndt T, Claussen U, Gssregen B, Schrfel S, Strzer B, Werle A et al (2011) Kratom alkaloids and O-desmethyltramadol in urine of a Krypton herbal mixture consumer

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The release of vasoactive intestinal peptide (VIP) and acetylcholine (Ach) by submucosal neurons stimulates the enterocyte and Cl enters by co-transport with sodium and potassium through the basolateral Na + -K + -2Cl channel