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Specific neurological symptoms usually then follow, often in the form of parkinsonism (lead-pipe or cogwheel rigidity, bradykinesia, and postural instability [8] ) with or without a typical hand tremor, masked facial expressions, slurred speech, ataxia (lack of coordination), or dystonia (twisting and repetitive movements of part of the body)

Additionally, glucosinolates undergo enzymatic conversion to amines (3, 5)

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We established that Fbx2 overexpression in primary neurons derived from Tg2576 transgenic mice, a well characterized AD mouse model (Hsiao et al., 1995), significantly promoted BACE1 degradation and reduced A production

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