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[DOI] [PubMed] [Google Scholar] 216.Ciancarelli I., De Amicis D., Di Massimo C., Di Scanno C., Pistarini C., DOrazio N., Tozzi Ciancarelli M.G

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As mentioned above, the immunological mechanisms underlying nave T cell activation and leading to the autoimmune attack to hepatocytes in AIH are initiated by presentation of autoantigenic peptides by antigen presenting cells (APC) to nave T cells, in the presence of appropriate co-stimulation by ligandligand (CD28 on Th0, CD80 on APC) interaction between the two cells [1]