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The effect of venlafaxine on behaviour, body weight and striatal monoamine levels on sleep-deprived female rats

Its unclear why, but one possibility is that hawthorn might have interacted with drugs the patients were taking

Alzheimer, A

[Abstract]2025 Sep 3;52(1):859

Dadsetan S, Balzano T, Forteza J, Cabrera-Pastor A, Taoro-Gonzalez L, Hernandez-Rabaza V, et al

Additionally, sleep deprivation upregulated intestinal tryptophan-kynurenine metabolism, increased intestinal wall permeability, promoted systemic inflammation, and compromised blood-brain barrier integrity