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Pediatric cancer model development is lagging behind adult tumor model development, which is why we focus this review on CNS tumors mutated for BRAF V600E which are more prevalent in the pediatric patient population

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Maternal vitamin B12 deficiency, exclusive breastfeeding, and a maternal diet low in vitamin B12 are associated with infant vitamin B12 deficiency, methylmalonic acidemia, and homocysteinemia (273)

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