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By inhibiting NNMT, it leads to an increase in intracellular levels of NAD+ (nicotinamide adenine dinucleotide), a critical coenzyme for cellular metabolism and mitochondrial energy production

In animal studies, IGF-1 deficiency has been associated with impaired neurologic development, suggesting that this hormone has specific roles in axonal growth and myelination

Vitamin C-Induced Epigenetic Modifications in Donor NSCs Establish Midbrain Marker Expressions Critical for Cell-Based Therapy in Parkinsons Disease

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10.7 Novel metabolic interactions among neurons, astrocytes, and microglia 10.7.1 Neuron: metabolon at the synapse Beyond relying on global somatic energy production, emerging evidence suggests the existence of localized metabolons within neurons, particularly at presynaptic terminals (Li and Sheng, 2022)

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