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doi:10.3945/an.116.012948 105

Selvamani S, Dailin DJ, Gupta VK, Wahid M, Keat HC, Natasya KH, et al

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18 Interestingly, reactive astrocytes are also implicated in psychiatric disorders such as posttraumatic stress disorder, 20 where MAOB plays a critical role not only in aberrant GABA synthesis but also in generating H 2 O 2 , further underscoring the pathological relevance of astrocyte-derived oxidative stress

Lower levels of key indole metabolites have been observed in MS patients, and their absence is linked to reduced AhR signaling and impaired gut barrier function [73]

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