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The concentrations of Bax and Bcl-2, as well as the Bax/Bcl-2 ratio in the mitochondrial fraction of the submandibular salivary glands of HFD rats, was significantly higher compared to the control group (29% p = 0.0092, 33% p = 0.0024, 58% p = 0.002, respectively)

Additionally, emotional behavior and central GABA receptor expression were regulated by Lactobacillus treatment in a mouse through the vagus nerve, which serves as a communication pathway between the brain and the gut ( Glutamate is an excitatory neurotransmitter in the brain

Li Z, Qian D, Yumin H, Zihan W, Wenjuan D, Yang L, Yueping D, Hongpeng W, Shaomin S, Chuan D, et al

Some probiotics, such as Lactobacillus acidophilus , can sense the changes in the intestinal environment, regulate the function of intestinal endocrine cells, and promote the secretion of gastrointestinal hormones such as glucagon-like peptide-1 (GLP-1) (Smith et al., 2019)

Iron supplementation aggravates periventricular cystic white matter lesions in newborn mice

doi: 10.1158/0008-5472.CAN-20-1541 54 PranziniEPardellaEMuccilloLLeoANesiISantiAet al