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doi:10.1016/B978-0-12-386933-3.00003-0

Promising, but still unproven at the level of evidence you'd want before calling it a first-line treatment

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The strongest clinical use cases are metabolic slowdown, fatigue, exercise intolerance, insulin resistance, and visceral fat in patients who have plateaued with diet and training alone

Two athletes with identical VOmax values, training volumes, and diets may respond differently to collagen peptide supplementation, because their connective-tissue genetics, inflammatory profiles, and gut-absorption kinetics differ

Less frequent sessions may be more effective Finding: Reducing microneedling session frequency (e.g., fortnightly rather than weekly) showed a positive influence on treatment outcomes