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Description

Mol Cell Biochem 480 , 139157 (2025)

Gut microbiotadependent trimethylamine N-oxide (TMAO) pathway contributes to both development of renal insufficiency and mortality risk in chronic kidney disease

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MGBA, Microbiota-Gut-Brain Axis

We performed 13 C 2 -acetylcarnitine tracing and found that around 58% of cellular acetyl-CoA is derived from supplemented acetylcarnitine (Extended Data Fig