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5a, b) (Suppl

There was no statistically significant improvement in MS during the 24-week treatment period in cohort 1 (rate of change = 0.05 dB/month, 95% CI: 0.07 to 0.17, P = 0.38) or cohort 2 (rate of change = 0.04 dB/month, 95% CI: 0.08 to 0.16 dB/month, P = 0.48), but in cohort 3, there was a statistically significant improvement in MS of 0.15 dB/month (95% CI: 0.040.26

Phagocyte-derived oxidants suppress the elastase-inhibitory capacity of alpha 1-proteinase inhibitor in vitro

A substantial improvement in dry eye-related quality of life scorea patient-reported measure of eye function, comfort, and symptomswas also reported in the 60 mg group (Hitoe 2014)

Yan R, Lin B, Jin W, Tang L, Hu S, Cai R

Recent studies suggest that ALA IV therapy may also benefit individuals with Non-Alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatitis (NASH)