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Serious vitamin B12 deficiency can cause cancer , nerve damage or anemia

Key mechanisms include: Stimulation of collagen and elastin synthesis in fibroblasts Activation of lysyl oxidase for collagen cross-linking Enhanced production of glycosaminoglycans and decorin Modulation of metalloproteinase activity for controlled matrix breakdown The copper ion serves as an essential cofactor for enzymes involved in collagen synthesis and provides antioxidant protection through superoxide dismutase activation

Maintaining blood glucose levels as close to normal as possible significantly reduced the risk of developing DPN and DAN

The bottom line is that B12 with MIC helps convert fat into energy, reduces fatigue, and boosts motivation to stay active

Wainwright P (2017) Q&A: Metformin and vitamin B12 deficiency

You can get them from a variety of foods, but even a carefully chosen diet may not provide the amounts of all the B vitamins you need, every single day