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Compared with control rats, total GRK6 expression is increased, and its distribution is reduced in the intercalated disks but increased in the cytoplasm of cardiac myocytes in spontaneously hypertensive heart failure rats [71]

Disclosure of interest: Yue Gu: nothing to disclose E-Posters - NOVEL TARGET/ EXPERIMENTAL FIDINGS TO CLINICAL TRANSLATION 06.00 - NOVEL TARGET/ EXPERIMENTAL FIDINGS TO CLINICAL TRANSLATION - 06.02 - GENETICS, OMICS AND BIOMARKERS P2578 - ESOC25-846 CEREBROVASCULAR REACTIVITY AT TRANSCRANIAL DOPPLER AS A POSSIBLE INDICATOR OF VASCULAR INJURY IN ALZHEIMERS DISEASE: CORRELATIONS BETWEEN BHI AND PLASMATIC BIOMARKERS Maria Rosaria Bagnato 1,2 , Martina Gaia Di Donna 1,2 , Chiara Giuseppina Bonomi 1 , Caterina Motta 1 , Alessandro Martorana 1 , Marina Diomedi 1 1 University of Tor Vergata Rome, Rome, Italy, 2 Stroke Unit Department Hospital F

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