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Surgical challenges after neoadjuvant chemo-immunotherapy: How to predict difficult cases

Alterations in external conditionssuch as dietary factors, chemical exposures, and psychological stressorsor cellular stress can induce changes in epigenetic marks, leading to gene transcription activation or silencing

In addition, treatment of DVT is aimed at preventing thrombus spread, cardiopulmonary failure, death, and long-term complications

This action helps regulate the hypothalamic-pituitary-gonadal (HPG) axis, which is crucial for maintaining reproductive hormone levels

Mitochondrial serine metabolism supports purine nucleotide synthesis, conferring 5-FU resistance by mitigating DNA damage, conversely, serine deprivation sensitizes CRC to 5-FU (193)

Like atomoxetine, it has a lower potential for misuse and abuse than stimulant medications