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PubMed, Li, Ling, et al

showed that resveratrol can inhibit NADPH oxidase 4 (NOX 4) (producing superoxide) and thus reduce its derived reactive oxygen species ROS, which can reduce the oxidative stress caused by radiation therapy 26

& Williams, H

Senescent TECs upregulate cyclin-dependent kinase inhibitor 2 A (p16), 1B (p27), and 1 A (p21) and secrete diverse cytokines and growth factors via the SASP

Given the significant impact of maternal age on reproductive outcomes and the emerging importance of these novel cell death pathways, strategies to enhance oocyte quantity and quality in women of advanced maternal age are of paramount importance in reproductive medicine

In contrast, ZDHHC9-mediated palmitoylation of cGAS at the 404/405 site is required for its dimerization and antiviral innate immunity signaling, and this process is inhibited by LYPLAL1 (69)