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The Alkaloids: Chemistry and Biology 63 : 45-86

10.1001/jamanetworkopen.2024.34180 172 LeeJ.WestD.PellegriniC.WeiJ.WilcoxS.Neils-StrunjasJ.et al (2025)

doi: 10.3389/fphys.2025.1606267 Received 05 April 2025 Accepted 02 September 2025 Published 22 September 2025 Volume 16 - 2025 Edited by Giovanna D'Arcangelo, University of Rome Tor Vergata, Italy Reviewed by Blake Graeme Perry, Massey University, New Zealand Bruce Rogers, University of Central Florida, United States Kang Chen, Tianjin University of Sport, China Updates Copyright 2025 Allison, Bedi, Rourke, Mizzi, Walsh, Heisz and Al-Khazraji

In the yeast enzyme, an active site Mg 2+ , orients the glutamate -carboxylate for attack on the -phosphate of ATP, which is positioned by a second Mg 2+ and an active site lysine

Plastic pollutants, particularly microplastics and nanoplastics, induce intestinal barrier dysfunction, dysbiosis, and metabolic abnormalities [170, 228, 229]