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Despite all these knowledge, there are documented drawbacks to fish oil use, which includes the presence of heavy metal contamination and antibiotics in fish sources (Sidhu, 2003), as well as smells and odors that are undesirable, issues with stability, high cost, and challenges in purifying because of the small levels of DHA and EPA fatty acids (Department of Forestry, Fisheries and the Environment (DFFE) et al., 2023)

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Surface alterations such as PEGylation or biomimetic coatings can prevent protein adsorption and opsonization, effectively shielding the nanoparticles from recognition by the mononuclear phagocyte system (Rampado et al., 2020

Algunos nutrientes actan como moduladores epigenticos que pueden optimizar estos niveles

Inject slowly. Which peptides are most often associated with injection-site reactions

Surface charge profoundly influences both BBB interactions and toxicity