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This suggests that CD4 + T cells play an important role in AIDs such as SLE through succinic acid accumulation, HIF-1 activation and mtROS production

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The CaMKII-Cre mice were kindly provided by Shigeyoshi Itohara (RIKEN Center for Brain Science)

Thus, SIRT1 is a direct target and it can be directly phosphorylated by AMPK

Group 2: n = 24

hi , SK-N-SH cells transfected with the CEBPD overexpression plasmid for 48 h led to increased CEBPD expression at both mRNA ( h ) and protein ( i ) levels, as determined by qPCR and immunoblotting

Electronic supplementary material 13054_2013_2880_MOESM1_ESM.docx (download DOCX Additional file 1: Table S1: Studies of glutamine supplementation in patients not included in the analysis