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Podratz Jewel L, Knight Andrew M, Ta Lauren E et al (2011) Cisplatin induced Mitochondrial DNA damage in dorsal root ganglion neurons

Pathological conditions caused by infection or disease can raise TF levels in the blood, which can then activate the coagulation mechanism (Reference Butenas49)

At this time it is unclear whether free radical involvement in Parkinson's disease is a primary or secondary event in nigral cell death or whether it occurs early or late in the disease process