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Cell death ratio ( a, b ) was assessed by using trypan blue exclusion assay (n = 5)

For instance, in oncology, 53.3% of new drugs developed between 1946 and 1980 were either natural products or derivatives thereof, with a reduced but still significant proportion of 33.5% from 1981 to the present (Newman and Cragg, 2020)

Conclusion We found that MSCs and HUVECs differed in their resistance to DMSO when used as a cryoprotectant, and that their DMSO tolerance depended on cell membrane fluidity and ROS resistance (Fig