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Niveaux dficients : En dessous de 200 pg/mL (148 pmol/L), cela indique une carence, qui peut provoquer des symptmes tels que la fatigue, lanmie et des problmes neurologiques

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Meat Poultry Fish Shellfish Dairy Fortified cereals Anemia B12 deficiency Cancer Cardiovascular disease Cognition Fatigue Vitamin B12 is involved in the transfer of methyl groups, and in methylation reactions essential for the synthesis of phospholipids and neurotransmitters in the central nervous system

For suspected macro-B12, precipitation with PEG is the test most often reached for, though it is nonspecific and can remove B12 that is fully available to cells, so direct measurement of the binding proteins, haptocorrin and transcobalamin, may be more informative when it is available