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Group 5 received local MSC and G-CSF via Hydrogel and an intravenous injection of MSC

Funding The authors receive support from the Veterans Administration (BX005382 to R.D.K.), Spanish Ministry of Science, Innovation, and Universities (Research-Grant: PID2022-1381850B-I00 to R.M.L

Everyone else benefits from a short clinician-led consultation before starting

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Concentration Guidelines: Standard range: 2% to 10% for skin applications Face, neck, and scalp applications: 4% concentration Eye area applications: 2% concentration (due to skin sensitivity) Typical dosage: One dollop of cream (approximately 50mg of GHK-Cu) Application Protocols: Serums: Apply to clean, dry skin 1-2 times daily without rinsing Face creams: Apply morning and night as part of daily skincare routine Shampoo/scalp products: Apply after washing hair, massaging deeply into the scalp For optimal results, consistent application over a period of three months may be necessary to observe noticeable improvements in skin health and rejuvenation

Khavinson and his collaborators have published the bulk of the existing research on it across roughly 25-30 years of work ranging from cell culture experiments through animal lifespan studies into human clinical observations