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Abstract P4-12-17: Pre-clinical data and phase I design for PQ-203: a novel peptide-drug conjugate (PDC) targeting the SORT1 receptor in hormone receptor Triple Negative Breast Cancer (TNBC)

113,114 In MASLD and MASH, E3 ligases play dual roles, with both protective and pathological implications

In more detail, nineteen studies deal with AD or MCI [16,20,23,29,36,39,40,41,42,43,44,45,46,47,48,49,50,51,52], three with vascular cognitive impairment (VCI) [53,54,55], five with HE [56,57,58,59,60], four with other secondary dementias [61,62,63,64], and six with an unspecified cognitive disorder [65,66,67,68,69,70]

In conclusion, mitochondrial OXPHOS is upregulated in glioblastoma upon glucose starvation

Additional research discussions may reference this compound in experimental models focused on cellular signaling behavior and metabolic pathway exploration