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doi: 10.1212/con.0000000000000313 72 PonomarevaE

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MASLD serves as an umbrella term that encompasses a broad spectrum of pathological liver changes from simple hepatic steatosis to steatohepatitis associated with metabolic dysfunction, which can lead to fibrosis and eventually progress to cirrhosis or hepatocellular carcinoma (HCC), while simultaneously increasing the risk of cardiovascular diseases (CVDs) and extrahepatic malignancies [1]

The risk and severity of CRS are influenced by tumor burden, CAR construct design, and T cell dose

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The invention herein described, by way of example only, with reference to the accompanying drawings, wherein: FIG