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Indeed, in our study on microglial cells we found that benfotiamine reduces activation of ERK1/2 and JNK, that being the probable route by which benfotiamine exerts its effects on actin cytoskeleton reorganization

The changes of MMPs were detected by JC-1

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Dyck, J.A., Maul, G.G., Miller, W.H., Chen, J.D., Kakizuka, A., Evans, R.M

While nitrogen metabolism was also over-represented in the FP group, most of the important metabolic pathways found were not related to amino acid metabolism